Announcement about the defense of Mamarozikov Umidjon Doctor of Philosophy (PhD) dissertation

Announcement

about the defense of Mamarozikov Umidjon Doctor of Philosophy (PhD) dissertation

I. General information.

Dissertation topic, specialization code (name of the field of study for which the degree is awarded): “Development of plant protection products based on Haplophyllum perforatum Juss., Juglans regia L. and Ailanthus altissima Mill. plants extracts”, 02.00.10 – Bioorganic chemistry (chemical sciences).

Dissertation topic registered number: B2024.2.PhD/K82

Supervisor: Khidirova Nazira Kudratovna

Dissertation prepared institution: Institute of the Chemistry of Plant Substances named after Acad. S.Y. Yunusov. AS RUz.

Institution where Scientific Council operates, Scientific Council number: Institute of the Chemistry of Plant Substances named after Acad. S.Y. Yunusov. AS RUz., DSc. 02/30.01.2020.K/T.104.01.

Opponents: doctor of chemical sciences, senior researcher  Nishanbayev Sabir Zaripbayevich, candidate of chemical sciens, dotsent   Maulyanov Salikhjan Alimjanovich

Leading organization:                         Bioorganic chemistry Institute

Dissertation direction: theoretical and practical.

II. The aim of the study The aim of the study is to study the chemical composition of dry extracts of the aerial parts of the plant Haplophyllum perforatum and leaves of Juglans regia, Ailanthus altissima, as well as the creation of “green pesticides” based on them.

III. The scientific novelty of the study is as follows:

For the first time, the optimal conditions for obtaining extracts of plants Haplophyllum perforatum, Juglans regia, Ailanthus altissima were determined, their chemical composition was studied by GC/MS, HPLC and CC methods. As a result, 90 compounds were identified, of which 63, in particular quercetin, dihydroquercetin, luteolin, rutin, cinaroside, salidroside, and others new for these plants, 12 compounds were individually isolated, the structures of which were proven by physico-chemical methods;

by studying the chemical composition of extracts of Juglans regia and Ailanthus altissima, 33 and 25 compounds were identified, respectively, of which 23 and 13 were discovered for the first time in these species;

the conditions for obtaining of a dry extract of the aerial part of the plant Haplophyllum perforatum have been determined, the optimal parameters of which are grinding the raw material to a size of 2-4 mm, triple extraction with ethyl alcohol at 35˚C, hydromodule 1:8 for 6 hours;

a standardized insecticidal agent was created, conventionally named “Haplocide” - based on an extract of the aerial part of the plant Haplophyllum perforatum L. for the first time, which is protected by a patent of the Republic of Uzbekistan

it has been established that leaf extracts of the Juglans regia plant exhibit herbicidal and insecticidal activity depending on the concentration of ethyl alcohol used as an extractant, which is explained by the amount of juglone and naphthalene they contain, as a result of which a 1% aqueous emulsion of the resulting dry extract is 40 % alcohol is recommended as a bioherbicide for the control of annual weeds.

IV. Implementation of the research results. Based on the scientific results obtained on the development of plant protection products based on plant extracts of Haplophyllum perforatum Juss., Juglans regia L. and Ailanthus altissima Mill:

a patent was received for an invention from the Intellectual Property Agency of the Republic of Uzbekistan for a product for protecting cultivated plants from insect pests (No. IAP 06610. 2021). As a result, it becomes possible to create a new environmentally friendly, effective bioinsecticide;

a patent for an invention was received from the Intellectual Property Agency of the Republic of Uzbekistan for a product with herbicidal properties based on the extract of Juglans regia leaves (No. IAP06871. 2022). As a result, it becomes possible to create an environmentally friendly, effective bioherbicide based on local plant materials;

an organization standard has been developed and approved (Ts 05535440-47:2022) for 1% w.e. extract of the aerial part of the plant Haplophyllum perforatum. As a result, it becomes possible to use domestic bioinsecticides based on local plants.

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